Related Items:berlie williams, bugaloo, Bugaloo’s Conch Crawl Rain continues, flooding stops business as usual Providenciales, 24 Feb 2015 – Bugaloo returns home to Providenciales today; see photos shared with us at Facebook. Berlie ‘Bugaloo’ Willliams was in Havana, Cuba where he underwent a successful spine surgery and is in recovery mode. The namesake of Bugaloo’s Conch Crawl in Five Cays has petitioned the public to help with his medical and home care expenses; you can donate at his bank account at RBC. Recommended for you Facebook Twitter Google+LinkedInPinterestWhatsApp Facebook Twitter Google+LinkedInPinterestWhatsApp Bugaloo’s Conch Crawl a Joaquin survivor Bugaloo returning to Provo Saturday, still needs financial help
© molekuul_be/Shutterstock.comAs reported in the journal AIDS, Dr Ruth Ruprecht and colleagues have shown in an animal model that immunoglobulin M (IgM) prevented infection after mucosal AIDS virus exposure.Globally, around 90% of new cases of HIV-1 infection arise through exposure to the virus in mucosal cavities such as the lining of the vagina or rectum.Related StoriesPrevalence of anal cancer precursors is higher in women living with HIV than previously reportedEven when HIV prevention drug is covered, other costs block treatmentHIV therapy leaves unrepaired holes in the immune system’s wall of defense”IgM is sort of the forgotten antibody. Most scientists believed its protective effect was too short-lived to be leveraged as any kind of protective shield against an invading pathogen like HIV-1,” says Ruprecht.For the study, six Rhesus monkeys were treated with a synthetic version of IgM, an antibody produced by plasma cells under the surface epithelium of bodily cavities. Thirty minutes later, the animals were exposed to simian-human immunodeficiency virus (SHIV).Ruprecht and colleagues report that following this exposure, four of the six animals were fully protected against infection with the virus. They found that treating the monkeys with IgM resulted in what is referred to as immune exclusion – the antibody agglutinates the virus and stops it from passing through the epithelial barrier into the bloodstream where it could then spread to other parts of the body.Ruprecht says IgM has a high affinity for its antigens, grabbing them very quickly and not letting go: “Our study reveals for the first time the protective potential of mucosal anti-HIV-1 IgM. IgM has a five-times higher ability to bind to virus particles compared to the standard antibody form called IgG. It basically opens up a new area of research. IgM can do more than it has been given credit.”In an accompanying editorial, Ruprecht’s work has been referred to as setting off a new wave in evaluating the activity of IgM antibodies in neutralizing HIV-1: “[She and her group] have largely broadened the horizon of neutralizing HIV-1 antibodies, which, as single or combined agents, may be used for HIV-1 prevention and treatment.”The article describing the new and exciting findings has been listed as “Fast Track,” due to the special attention it should receive and generate. Source: https://eurekalert.org/pub_releases/2018-07/tbri-rsa072318.php By Sally Robertson, B.Sc.Jul 24 2018A team of scientists from Texas Biomedical Research Institute have homed in on an antibody that could protect against infection with HIV-1.
[dropcap]C[/dropcap]ome on down – the price is right……As documented in an earlier column – I always think it’s important for the punter to have an idea what a price SHOULD be and then compare this to the actual odds.This is the complete opposite approach of most punters who look at the odds and THEN try to fit a bet around them.Good case in point is the Norwich v Spurs game today (4pm. Sky). I was fully expecting Spurs to be odds-on for this – so was naturally surprised to see them odds against and have to bet accordingly with Star Sports.Spurs are very much still pushing for a top four finish in the Premier League whilst the Canaries are perilously placed right next to the relegation line and have really struggled to score goals this season, especially at home where their average is just 0.84 goals per game !.Norwich have won only one of their last 11 matches and were brushed aside by Spurs in the reverse fixture in September.HEAD TO HEAD RECORD(Max last 10 only)Sep 2013 Premier Tottenham 2-0 NorwichJan 2013 Premier Norwich 1-1 TottenhamOct 2012 Capital One Norwich 2-1 TottenhamSep 2012 Premier Tottenham 1-1 NorwichApr 2012 Premier Tottenham 1-2 NorwichDec 2011 Premier Norwich 0-2 TottenhamDec 2004 Premier Norwich 0-2 TottenhamSep 2004 Premier Tottenham 0-0 NorwichApr 1995 Premier Tottenham 1-0 NorwichDec 1994 Premier Norwich 0-2 TottenhamThe irony of today’s match is that a Norwich defeat could mark the end of Chris Hughton’s tenure at Carrow Road. He is already odds-on to be the next Premier League manager to get the boot (or ‘leave his position’ as is more politically correct these days). Hughton, of course, has a long history with Spurs both as a player and as part of the management team but there will be no place for sentiment this afternoon from Spurs who could draw level with Liverpool in the table.Norwich need points and they need them now. They have an astonishing end to the season with their final four matches against Liverpool, Manchester United, Chelsea and Arsenal !!Spurs are continuing to play good football under Tim Sherwood and only Chelsea have a better record in the Premier League since he took the helm.Snap up the odds against for another win that might well condemn Hughton.RECOMMENDED BET (1-10 points)10 points SPURS at around 11/10 with Star SportsRUNNING RETURN (FEBRUARY): LOSS 41.91 POINTSRUNNING RETURN (YEAR): LOSS 31.19 POINTSWhat’s your view? CALL STAR SPORTS 08000 521 321