Individuals with herpes have reported seemingly unrelated symptoms such as constipation and urinary retention (inability to empty the bladder), but the mechanism was not understood. So the research team decided to investigate using mice models of herpes simplex virus-1, the dominant cause of genital herpes in the US.They found that the herpes virus spread from the genitals to nerves in the spinal chord, and then on to neurons in the colon, killing them. The damage to the colonic neurons prevented the movement of food along the digestive tract, leading to an enlarged colon and disease. Also Read – ‘Playing Jojo was emotionally exhausting’“The key findings is that there is this unexpected infection in the neurons in the colon wall after herpes infection,” said lead researcher Akiko Iwasaki, professor of immunobiology at Yale School of Medicine in New Haven, Connecticut, US. The findings were published in the journal Cell Host & Microbe.“Other members of the herpes virus family, including Epstein-Barr virus, chicken pox virus, and cytomegalovirus have been found in the neurons of the colon of people with unexplained chronic constipation,” Iwasaki, who is also an investigator at Maryland-based non-profit Howard Hughes Medical Institute, said.“When doctors can’t figure out the cause of these chronic intestinal conditions, one thing to look at is a viral infection,” she explained.
KOLKATA: Tension was triggered after Member of Parliament (MP) in Rajya Sabha Dr Santanu Sen was allegedly threatened by some unknown persons over phone. He lodged a complaint with the Sinthi police station in this regard on Saturday.According to the complaint lodged by Sen, he has been receiving threat calls from unknown numbers, stating that they would kill him. Sen alleged that three callers were using the same number to threaten him. Some other numbers were also used to threaten him with dire consequences. Also Read – Bose & Gandhi: More similar than apart, says Sugata BoseAccording to sources, Sen was getting such calls since almost one and a half months. Initially, he did not pay any attention to the calls but the problem escalated since the last few weeks. It was alleged that he was getting threats frequently. Sen alleged that sometimes, the caller told him that he would be killed. He was told that his family members would be killed as well. During the last two calls, he was told that explosives will be placed near his residence to blow up the house. Also Read – Rs 13,000 crore investment to provide 2 lakh jobs: MamataLater, Sen informed the Officer on Special Duty (OSD) to Chief Minister Mamata Banerjee about the phone calls. Following that, he lodged a complaint with Sinthi police station, narrating the whole incident. He also stated that he is not afraid of such calls but intimated the police to act accordingly. He also provided the mobile numbers to the investigating officers. Based on Sen’s complaint, an FIR has been initiated on charges of 506 IPC (punishment for criminal intimidation) and 34 IPC (acts done by several persons in furtherance of common intention) against unknown persons. Till Sunday night, no one has been arrested in the case. Sleuths are trying to get the details of the phone numbers which were used to threaten Sen. Police are also trying to locate the tower location of the mobile numbers.
“Selfitis” – the obsession of taking selfies on smartphones – may be a real disorder that requires treatment, according to a study conducted in India. Researchers at Nottingham Trent University in the UK and the Thiagarajar School of Management (TSM) in Tamil Nadu began investigating the phenomenon after a hoax story appeared in the media in 2014 claiming ‘selfitis’ had been classed as a genuine mental disorder by the American Psychiatric Association. They have now confirmed its existence and developed the ‘Selfitis Behaviour Scale’ which can be used to assess its severity.The scale was developed using a large number of focus groups with 200 participants and the scale was tested via a survey of 400 participants.Participants were based in India because the country has the most users on Facebook, as well as the highest number of deaths as a result of trying to take selfies in dangerous locations.The findings, published in the International Journal of Mental Health and Addiction confirmed that there are three levels of selfitis. Borderline is defined as taking selfies at least three times a day but not posting them on social media.Acute selfitis describes taking selfies at least three times a day and posting each one on social media.Chronic selfitis is the uncontrollable urge to take photos of one self round the clock and posting the photos on social media more than six times a day, researchers said.Six motivating factors were identified, with selfitis sufferers typically seeking to increase their self-confidence, seek attention, improve their mood, connect with the environment around them (to create a record of memories), increase their conformity with the social group around them, as well as being socially competitive.The prevalence of these factors determined the level of selfitis severity.”A few years ago, stories appeared in the media claiming that the condition of selfitis was to be classed as a mental disorder by the American Psychiatric Association,” said Mark Griffiths, from Nottingham Trent University.”While the story was revealed to be a hoax, it did not mean that the condition of selfitis did not exist,” Griffiths said.”We have now appeared to confirm its existence and developed the world’s first Selfitis Behaviour Scale to assess the condition,” he said.”Typically, those with the condition suffer from a lack of self-confidence and are seeking to ‘fit in’ with those around them, and may display symptoms similar to other potentially addictive behaviours,” said Janarthanan Balakrishnan, assistant professor at TSM.”Now the existence of the condition appears to have been confirmed, it is hoped that further research will be carried out to understand more about how and why people develop this potentially obsessive behaviour, and what can be done to help people who are the most affected,” he said.
Opinions expressed by Entrepreneur contributors are their own. Free Webinar | Sept. 9: The Entrepreneur’s Playbook for Going Global Register Now » Every small business loves the exposure, empathy and sense of community that having a website that’s a daily destination for consumers can generate. But getting people to visit on a regular basis can be a challenge, especially if updates are infrequent or all you have to offer is the occasional monotone press release or product announcement. Thankfully, building a website that’s “sticky” enough to keep users engaged and coming back doesn’t have to require investing thousands or reinventing yourself as the next online media empire. All it takes is a little elbow grease and personal touch, as indicated by the simple strategies below, each designed to send your homepage’s daily number of visitors soaring:Connect and Communicate: Make no bones about it: Blogging should be an essential part of any modern website. After all, a few clicks is literally all it takes to post updates in real-time around the clock, creating a steady stream of content that promises something new and exciting with every visit. Better still, professionals at all experience levels have the capability of readily doing it, and the practice also helps put a personal face on your organization, shining the spotlight on the individuals behind it. However, to really captivate an audience enough to keep them returning, take note: You’ll also need to provide content that’s dynamic, unique and offers measurable informational or entertainment value, plus speak in a language that all can understand. In short, the occasional pre-approved sound bite from the HR guy or gal won’t cut it. Rather, you need to address audiences like you’re having a normal conversation, and provide content with meaningful substance to the reader. Making-of articles, features detailing how to get more from your products, partner profiles, project diaries, step-by-step how-to guides, interviews with notable personalities or internal stakeholders: All present compelling ways to connect with audiences while also keeping them interested and informed, providing ample incentive to keep coming back.Emphasize Community Building: As social media insiders well know, creating a sense of community around your website is one of the most powerful tools for engaging and ultimately enthralling prospective fans. But doing so doesn’t simply mean throwing up a sponsored message board then leaving it to stagnate, or e-mailing customers sporadic newsletter updates that regurgitate existing material easily found elsewhere. Rather, you have to not only encourage discussion and actively take part in conversations by dedicating internal time and resources, but also make customers feel as if they truly have a voice in the discussion by listening to their concerns, responding and sourcing feedback at every opportunity. Implementing programs that recognize and reward valued contributors is also vital, as is creating fan-based initiatives that allow community members to contribute and share ideas, concepts and creations of their own. Even simply giving enthusiasts the chance to submit designs for your next fundraiser’s logo or arranging times where they can chat with top execs to provide input on upcoming ventures won’t just engender goodwill. They’ll also excite and empower a legion of amateur brand ambassadors–an essential source of free ongoing updates and constructive conversations, which will both attract users to and keep them enamored with your site.Design for Mass Distribution: Sharing is good–even more so if you’ve got a message worth spreading and it winds up in front of millions of eyeballs. As such, you should be not only updating your website with unique pieces of content (surveys, research reports, custom editorial clips, guides to solving common problems, unique looks behind-the-scenes, etc.) designed to grab viewers’ attention, but also making everything from blog posts to pictures, photos, PDF documents and videos shareable, embeddable and ready to be commented upon or re-tweeted via social media platforms. When it comes to corporate assets, the tendency–especially among hyper-competitive start-ups–is always to tightly hold and control. But often, the more powerful strategy is to design pieces of content with the specific idea in mind of seeding them throughout the user community, as it’s a great way to build brand awareness. Beyond heightened exposure and additional media mentions, using your website to disseminate unique, specially branded pieces of content can also lead to improved search engine optimization results through a larger number of incoming links. And, more important still, generate heightened word of mouth surrounding your homepage, letting countless potential readers know exciting things are happening there on a regular basis.Focus on Value: Exclusive specials, contests, promotions and timed discounts can all be powerful drivers of website traffic, especially in these cost-conscious times. By offering direct bargains and rebate programs on both an ongoing and sporadic basis through your online headquarters, you can keep customers’ interest piqued, and generate additional sales. These marketing programs become even more valuable when coupled with Facebook, Twitter and other social marketing tools, which have the potential to help news spread like wildfire online. Just make sure that the only place such bargains can be found is on your homepage, and be consistent in terms of the pages to which you drive this traffic, to establish in shoppers’ minds the importance of regularly checking a certain destination. Similarly, establishing relationships with key bloggers and members of the media can also help reinforce the message, as can a regular series of e-mail or newsletter updates designed to inform current and prospective buyers. Customers get to save on purchases while you benefit from enhanced publicity and heightened sales, creating a win-win situation for all.Use Targeted Demonstrations: While special membership options, premium subscription packages and frequent buyer programs can all prove great incentives, services that you freely give away are often just as important as those that you reserve for more exclusive clients. Whether you’re looking at offering complimentary computer virus scans by having users visit your homepage, providing a suite of free continuing education resources or simply hosting an archive of complementary, corporate-branded webinars on software engineering, realize: Providing helpful services or information at no charge that solve pressing, evergreen problems or answer important questions can all serve to generate a steady source of online traffic, and provide a ready supply of leads to upsell on premium services. Sometimes you have to give in order to get. It may seem counterintuitive, but ultimately, the practice makes a ready way to demonstrate your organization’s capabilities to a potentially lucrative client base, while also giving them a taste of the benefits to be had by partnering on more advanced or long-term services. Growing a business sometimes requires thinking outside the box.
Register Now » 1 min read Apple diehards will soon have the chance to own a formative piece of the company’s history, when one of the very first Apple 1 computers is auctioned off on October 22.The Apple 1, which marks the storied company’s inaugural product, was concocted by Steve Wozniak in either Steve Jobs’ family garage or in his little sister’s bedroom.The still-functioning motherboard, which will be offered by Bonhams New York, is expected to fetch between $300,000 and $500,000, according to the auction house. For comparison’s sake, when the product was first introduced in 1976, it was sold for a rather ominous $666.66.While the Apple 1 computer singlehandedly “[heralded] the dawn of the personal computer revolution,” according to Bonhams, only 200 units were ever made — roughly 15 of which are still operational today.Related: Apple Reportedly Delays Launch of Jumbo iPad October 9, 2014 Free Webinar | Sept. 9: The Entrepreneur’s Playbook for Going Global Growing a business sometimes requires thinking outside the box.